MacDougald Lab
John A. Faulkner Collegiate Professor Award Ceremony
Ormond A. MacDougald, Ph.D., professor of Molecular and Integrative Physiology and Internal Medicine (Metabolism, Endocrinology & Diabetes Division) in the University of Michigan Medical School, is the inaugural recipient of the John A. Faulkner Collegiate Professorship in Physiology.
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In The News
Inhibiting Fat

Genetically engineered mice, created at the UM Medical School, are living every dieter's dream.

They eat unlimited amounts of high-fat mouse chow, but have about 50 percent less body fat than normal mice on a low-fat diet. And they show no signs of diabetes or other metabolic disorders, which are common in animals with too little fat.   read more >

Journal Covers & Popular Press


 
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Microarray Data
microarray Wnt signaling maintains preadipocytes in an undifferentiated state. When Wnt signaling is
enforced, 3T3-L1 preadipocytes no longer undergo adipocyte conversion in response to adipogenic medium. Here we used microarray analyses to identify subsets of genes whose expression is aberrant when differentiation is blocked through enforced Wnt signaling. Furthermore, we used the microarray data to identify potentially important adipocyte genes and chose one of these, the liver X receptor alpha (LXRalpha), for further analyses.   read more >

 
 

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