John A. Faulkner Collegiate Professor Award Ceremony
Ormond A. MacDougald, Ph.D., professor of Molecular and Integrative Physiology and Internal Medicine (Metabolism, Endocrinology & Diabetes Division) in the University of Michigan Medical School, is the inaugural recipient of the John A. Faulkner Collegiate Professorship in Physiology.
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In The News
Inhibiting Fat
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Genetically engineered mice,
created at the
UM Medical School, are living every dieter's dream.
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They
eat unlimited amounts of high-fat mouse chow, but
have about 50 percent less body fat than normal
mice on a low-fat diet. And they show no signs of
diabetes or other metabolic disorders, which are
common in animals with too little fat. read more > |
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Microarray Data
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Wnt signaling maintains preadipocytes in an undifferentiated
state. When Wnt signaling is |
enforced, 3T3-L1 preadipocytes
no longer undergo adipocyte conversion in response
to adipogenic medium. Here we used microarray analyses
to identify subsets of genes whose expression is
aberrant when differentiation is blocked through enforced Wnt signaling. Furthermore, we
used the microarray data to identify potentially
important adipocyte genes and chose one of these,
the liver X receptor alpha (LXRalpha), for further
analyses. read more
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